PhD, Eidgenossische Technische Hochschule (ETH Zurich) (2018)
Broadly, my research focuses on harnessing nanophotonics, the study and manipulation of light on the nanoscale, to bridge engineering and biomedicine.
My core postdoctoral research develops nanostructured surfaces, known as “metasurfaces,” that enhance the scattering of light from a patient’s biopsied tissue or cell sample in order to quickly and accurately inform both the stage of a patient’s disease and the appropriate treatment. This all-optical, label-free technology has the potential to enable real-time tissue diagnostics of important diseases including cancer, Alzheimer’s disease and heart disease in the operating room or at the point-of-care.
Additionally, I am exploring chiral light-matter interactions on the nanoscale. Chirality, the phenomenon of handedness, describes structures which are non-superimposable upon their mirror image. Building on my doctoral research, where I theoretically and experimentally investigated the underlying physical mechanism by which chiral light interacts with optical antennas, in my postdoctoral training I continue to investigate this line of research in collaborative projects focusing on dielectric metasurfaces, which have applications in the development of pharmaceuticals free of side-effects and the transition to agrochemicals with improved environmental sustainability.
Poulikakos, L. V.; Dionne, J. A.; Garcia-Etxarri, A., Optical Helicity and Optical Chirality in Free Space and in the Presence of Matter, Symmetry 2019, 11(9), Cover Article Sept. 2019
Poulikakos, L.V. Chiral Light-Matter Interactions in the Near and Far Field. Doctoral Thesis, ETH Zurich (2018).Schnoering, G.; Poulikakos, L. V.; Rosales-Cabara, Y.; Canaguier-Durand, A.; Norris, D. J.; Genet, C. Three-Dimensional Enantiomeric Recognition of Optically Trapped Single Chiral Nanoparticles. Physical Review Letters, 121, 023902 (2018). Heeg, S.; Shi, L.; Poulikakos, L. V.; Pichler, T; Novotny, L. Carbon Nanotube Chirality Determines Properties of Encapsulated Linear Carbon Chain. Nano Letters, 18, 5426-5431 (2018). Poulikakos, L. V., Thureja, P.; Stollmann, A.; De Leo, E.; Norris, D. J. Chiral Light Design and Detection Inspired by Optical Antenna Theory. Selected to be featured as cover article August 2018. Nano Letters, 18, 4633–4640 (2018). De Leo, E.; Cocina, A.; Tiwari, P.; Poulikakos, L. V.; Gallego, P. M.; le Feber, B.; Norris, D. J.; Prins, F. Polarization Multiplexing of Fluorescent Emission Using Multi-Resonant Plasmonic Antennas. ACS Nano, 11, 12167–12173 (2017). Poulikakos, L. V.; Gutsche, P.; McPeak, K. M.; Burger, S.; Niegemann, J.; Hafner, C.; Norris, D. J. Optical Chirality Flux as a Useful Far-Field Probe of Chiral Near Fields. ACS Photonics, 9, 1619–1625 (2016). Gutsche, P.; Poulikakos, L. V.; Hammerschmidt, M.; Burger, S.; Schmidt, F. Time-Harmonic Optical Chirality in Inhomogeneous Space. Proceedings SPIE 9756, Photonic and Phononic Properties of Engineered Nanostructures VI, 97560X (2016). McPeak, K. M.; van Engers, C. D.; Bianchi, S.; Rossinelli, A.; Poulikakos, L. V.; Bernard, L.; Herrmann, S.; Kim, D. K.; Burger, S.; Blome, M.; Jayanti, S. V.; Norris, D. J. Ultraviolet Plasmonic Chirality from Colloidal Aluminum Nanoparticles Exhibiting Charge-Selective Protein Detection. Advanced Materials, 27, 6244–6250 (2015).
Akselrod, G. M.; Prins, F.; Poulikakos, L. V.; Lee, E. M. Y.; Weidman, M. C.; Mork, A. J.; Willard, A. P.; Bulovic, V.; Tisdale, W. A. Subdiffusive Exciton Transport in Quantum Dot Solids. Nano Letters, 6, 3556–3562 (2014).Poulikakos, L. V.; Prins, F.; Tisdale, W. A. Transition from Thermodynamic to Kinetic-Limited Excitonic Energy Migration in Colloidal Quantum Dot Solids. The Journal of Physical Chemistry C, 15, 7894–7900 (2014). Kierzkowska, A. M.; Poulikakos, L. V.; Broda, M., Muller, C. R. Synthesis of Calcium-Based, Al2O3-Stabilized Sorbents for CO2 Capture Using a Co-Precipitation Technique. International Journal of Greenhouse Gas Control, 15, 48–54 (2013).